5-Amino-1MQ (5mg)

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a small molecule inhibitor of
NNMT (Nicotinamide N-methyltransferase), an enzyme highly expressed in adipose
tissue that plays a central role in cellular metabolic regulation and the NAD+
salvage pathway.

Compound Details (per vial):
— 5-Amino-1MQ: 5mg
— Form: Lyophilized powder
— Purity: ≥98%

NNMT has emerged as a significant research target in metabolic disease, obesity,
and cancer biology. By inhibiting NNMT, 5-Amino-1MQ is studied for its ability
to raise intracellular SAM (S-adenosylmethionine) and NAD+ levels in adipocytes,
driving fat cell differentiation research and energy expenditure modeling. Studies
have also explored its role in reversing diet-induced obesity in murine models
without caloric restriction. Researchers studying the intersection of epigenetic
methylation, adipogenesis, and metabolic syndrome use 5-Amino-1MQ as a selective
NNMT inhibitor with high cell permeability.

Supplied lyophilized in a sterile sealed vial. Third-party tested for identity
and purity prior to release. Not for human consumption. For research use only.