Methylcobalamin is the neurologically active form of Vitamin B12, a water-soluble
essential vitamin involved in one-carbon metabolism, myelin synthesis, and
DNA methylation research.
Compound Details (per vial):
— Methylcobalamin (B12): 1mg/1ml
— Form: Sterile liquid solution
— Purity: ≥98%
Methylcobalamin is the biologically active coenzyme form of B12, distinguished
from cyanocobalamin by its direct availability for metabolic utilization without
hepatic conversion. In neurological research, methylcobalamin is studied for
its role in myelin sheath synthesis and maintenance, axonal regeneration,
and Schwann cell proliferation models. At the biochemical level, it functions
as a cofactor for methionine synthase in the remethylation of homocysteine
to methionine, making it essential in one-carbon metabolism and SAM-dependent
methylation reactions. It is of particular research interest in GLP-1 receptor
agonist studies, where clinical data has consistently documented B12 depletion
as a downstream effect of GLP-1 therapy due to reduced intrinsic factor
secretion. Research models studying metabolic syndrome, neuropathy, and
methylation pathway dysfunction frequently utilize methylcobalamin as both
an intervention compound and a biomarker reference point.
Supplied as a sterile sealed 1ml single-use vial. Third-party tested for
identity and purity prior to release. Not for human consumption.
For research use only.
cifafik217 –
Works great!