Semax is a synthetic heptapeptide analog of the ACTH(4-10) fragment, stabilized by a C-terminal Pro-Gly-Pro extension. It is studied for its effects on neurotrophic factor expression and neuroprotective signaling in preclinical models.
Full Product Description Semax (Met-Glu-His-Phe-Pro-Gly-Pro) was developed as a metabolically stabilized derivative of the ACTH(4-7) sequence. The addition of the Pro-Gly-Pro tripeptide increases resistance to enzymatic degradation while removing the steroidogenic activity of the parent hormone fragment.
Research has focused on Semax primarily for its influence on brain-derived neurotrophic factor (BDNF) and related neurotrophin pathways. Studies have examined its effects on BDNF and TrkB expression in hippocampal models, its activity in cerebral ischemia research, and its modulation of monoaminergic systems. It is frequently evaluated alongside Selank in cognitive and neuroprotective research frameworks due to their complementary profiles.
Supplied lyophilized in a sterile sealed vial. Third-party tested for identity and purity prior to release. Not for human consumption. For research use only.
Compound Details — Compound: Semax (ACTH(4-7)-Pro-Gly-Pro) — Sequence: Met-Glu-His-Phe-Pro-Gly-Pro — Vial Content: 10mg — Form: Lyophilized powder
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